274d: Difference between revisions

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[[Image:274d.gif|left|200px]]
[[Image:274d.gif|left|200px]]


{{Structure
<!--
|PDB= 274d |SIZE=350|CAPTION= <scene name='initialview01'>274d</scene>, resolution 2.300&Aring;
The line below this paragraph, containing "STRUCTURE_274d", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)
|LIGAND= <scene name='pdbligand=ANT:ANTHRAMYCIN'>ANT</scene>, <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY=  
or leave the SCENE parameter empty for the default display.
|GENE=  
-->
|DOMAIN=
{{STRUCTURE_274d| PDB=274d  | SCENE= }}  
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=274d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=274d OCA], [http://www.ebi.ac.uk/pdbsum/274d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=274d RCSB]</span>
}}


'''CRYSTAL STRUCTURE OF A COVALENT DNA-DRUG ADDUCT: ANTHRAMYCIN BOUND TO C-C-A-A-C-G-T-T-G-G, AND A MOLECULAR EXPLANATION OF SPECIFICITY'''
'''CRYSTAL STRUCTURE OF A COVALENT DNA-DRUG ADDUCT: ANTHRAMYCIN BOUND TO C-C-A-A-C-G-T-T-G-G, AND A MOLECULAR EXPLANATION OF SPECIFICITY'''
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==About this Structure==
==About this Structure==
274D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=274D OCA].  
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=274D OCA].  


==Reference==
==Reference==
Crystal structure of a covalent DNA-drug adduct: anthramycin bound to C-C-A-A-C-G-T-T-G-G and a molecular explanation of specificity., Kopka ML, Goodsell DS, Baikalov I, Grzeskowiak K, Cascio D, Dickerson RE, Biochemistry. 1994 Nov 22;33(46):13593-610. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7947769 7947769]
Crystal structure of a covalent DNA-drug adduct: anthramycin bound to C-C-A-A-C-G-T-T-G-G and a molecular explanation of specificity., Kopka ML, Goodsell DS, Baikalov I, Grzeskowiak K, Cascio D, Dickerson RE, Biochemistry. 1994 Nov 22;33(46):13593-610. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7947769 7947769]
[[Category: Protein complex]]
[[Category: Baikalov, I.]]
[[Category: Baikalov, I.]]
[[Category: Cascio, D.]]
[[Category: Cascio, D.]]
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[[Category: Grzeskowiak, K.]]
[[Category: Grzeskowiak, K.]]
[[Category: Kopka, M L.]]
[[Category: Kopka, M L.]]
[[Category: b-dna]]
[[Category: B-dna]]
[[Category: complexed with drug]]
[[Category: Complexed with drug]]
[[Category: double helix]]
[[Category: Double helix]]
[[Category: modified]]
[[Category: Modified]]
 
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