2ao7: Difference between revisions
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'''Adam10 Disintegrin and cysteine- rich domain''' | '''Adam10 Disintegrin and cysteine- rich domain''' | ||
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[[Category: Saha, N.]] | [[Category: Saha, N.]] | ||
[[Category: Wimmer-Kleikamp, S H.]] | [[Category: Wimmer-Kleikamp, S H.]] | ||
[[Category: | [[Category: Disintegrin]] | ||
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 19:16:48 2008'' | |||
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Revision as of 16:16, 3 May 2008
Adam10 Disintegrin and cysteine- rich domain
Overview
Ephrin ligands presented on one cell surface associate with their receptors on the surface of a juxtaposed cell, often resulting in cell-cell repulsion. In this issue of Cell, Janes et al. (2005) show that the ephrin ligand can be proteolytically released from its membrane tether by a complex on the opposing cell composed of the ephrin receptor and an ADAM metalloprotease.
About this Structure
2AO7 is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
ADAM and Eph: how Ephrin-signaling cells become detached., Mancia F, Shapiro L, Cell. 2005 Oct 21;123(2):185-7. PMID:16239135 Page seeded by OCA on Sat May 3 19:16:48 2008
