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'''NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1''' | '''NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1''' | ||
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==About this Structure== | ==About this Structure== | ||
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G1W OCA]. | |||
==Reference== | ==Reference== | ||
NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1: new insights into the recoding event of the ribosomal trans-translation., Nonin-Lecomte S, Felden B, Dardel F, Nucleic Acids Res. 2006 Apr 4;34(6):1847-53. Print 2006. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16595798 16595798] | NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1: new insights into the recoding event of the ribosomal trans-translation., Nonin-Lecomte S, Felden B, Dardel F, Nucleic Acids Res. 2006 Apr 4;34(6):1847-53. Print 2006. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16595798 16595798] | ||
[[Category: Dardel, F.]] | [[Category: Dardel, F.]] | ||
[[Category: Nonin-Lecomte, S.]] | [[Category: Nonin-Lecomte, S.]] | ||
[[Category: | [[Category: Nmr]] | ||
[[Category: | [[Category: Pk1]] | ||
[[Category: | [[Category: Pseudoknot]] | ||
[[Category: | [[Category: Tmrna]] | ||
[[Category: | [[Category: Trans-translation]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 04:36:13 2008'' | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | |||
Revision as of 01:36, 4 May 2008
NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1
Overview
The transfer-messenger RNA (tmRNA) pseudoknot PK1 is essential for bacterial trans-translation, a ribosomal rescue mechanism. We report the solution structure of PK1 from Aquifex aeolicus, which despite an unprecedented small number of nucleotides and thus an unprecented compact size, displays a very high thermal stability. Several unusual structural features account for these properties and indicate that PK1 belongs to the class of ribosomal frameshift pseudoknots. This suggests a similarity between the mechanism of programmed ribosomal frameshifting and trans-translation.
About this Structure
Full crystallographic information is available from OCA.
Reference
NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1: new insights into the recoding event of the ribosomal trans-translation., Nonin-Lecomte S, Felden B, Dardel F, Nucleic Acids Res. 2006 Apr 4;34(6):1847-53. Print 2006. PMID:16595798 Page seeded by OCA on Sun May 4 04:36:13 2008
