2hmr: Difference between revisions

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[[Image:2hmr.gif|left|200px]]
[[Image:2hmr.gif|left|200px]]


{{Structure
<!--
|PDB= 2hmr |SIZE=350|CAPTION= <scene name='initialview01'>2hmr</scene>
The line below this paragraph, containing "STRUCTURE_2hmr", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)
|LIGAND= <scene name='pdbligand=2EG:2&#39;-DEOXY-N-ETHYLGUANOSINE+5&#39;-PHOSPHATE'>2EG</scene>, <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY=  
or leave the SCENE parameter empty for the default display.
|GENE=  
-->
|DOMAIN=
{{STRUCTURE_2hmr| PDB=2hmr  | SCENE= }}  
|RELATEDENTRY=[[2hli|2HLI]], [[2hmd|2HMD]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hmr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hmr OCA], [http://www.ebi.ac.uk/pdbsum/2hmr PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2hmr RCSB]</span>
}}


'''Solution structure of reduced interstrand cross-link arising from S-alpha-methyl-gamma-OH-1,N2-propano-2'-deoxyguanosine in the 5'-CpG-3' DNA sequence'''
'''Solution structure of reduced interstrand cross-link arising from S-alpha-methyl-gamma-OH-1,N2-propano-2'-deoxyguanosine in the 5'-CpG-3' DNA sequence'''
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==About this Structure==
==About this Structure==
2HMR is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HMR OCA].  
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HMR OCA].  


==Reference==
==Reference==
Stereochemistry modulates the stability of reduced interstrand cross-links arising from R- and S-alpha-CH3-gamma-OH-1,N2-propano-2'-deoxyguanosine in the 5'-CpG-3' DNA sequence., Cho YJ, Kozekov ID, Harris TM, Rizzo CJ, Stone MP, Biochemistry. 2007 Mar 13;46(10):2608-21. Epub 2007 Feb 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17305317 17305317]
Stereochemistry modulates the stability of reduced interstrand cross-links arising from R- and S-alpha-CH3-gamma-OH-1,N2-propano-2'-deoxyguanosine in the 5'-CpG-3' DNA sequence., Cho YJ, Kozekov ID, Harris TM, Rizzo CJ, Stone MP, Biochemistry. 2007 Mar 13;46(10):2608-21. Epub 2007 Feb 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17305317 17305317]
[[Category: Protein complex]]
[[Category: Cho, Y J.]]
[[Category: Cho, Y J.]]
[[Category: Harris, T M.]]
[[Category: Harris, T M.]]
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[[Category: Rizzo, C J.]]
[[Category: Rizzo, C J.]]
[[Category: Stone, M P.]]
[[Category: Stone, M P.]]
[[Category: crotonaldehyde interstrand dna cross-link]]
[[Category: Crotonaldehyde interstrand dna cross-link]]
 
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