2i6e: Difference between revisions
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'''Crystal structure of protein DR0370 from Deinococcus radiodurans, Pfam DUF178''' | '''Crystal structure of protein DR0370 from Deinococcus radiodurans, Pfam DUF178''' | ||
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[[Category: Swaminathan, S.]] | [[Category: Swaminathan, S.]] | ||
[[Category: Tyagi, R.]] | [[Category: Tyagi, R.]] | ||
[[Category: | [[Category: Hypothetical protein,pfam:duf178]] | ||
[[Category: | [[Category: New york structural genomix research consortium]] | ||
[[Category: | [[Category: Nysgxrc,10093b]] | ||
[[Category: | [[Category: Protein structure initiative]] | ||
[[Category: | [[Category: Psi-2]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: | [[Category: Unknown function]] | ||
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Revision as of 04:07, 4 May 2008
Crystal structure of protein DR0370 from Deinococcus radiodurans, Pfam DUF178
Overview
BACKGROUND: Pfam is a comprehensive collection of protein domains and families, with a range of well-established information including genome annotation. Pfam has two large series of functionally uncharacterized families, known as Domains of Unknown Function (DUFs) and Uncharacterized Protein Families (UPFs). RESULTS: Crystal structures of two proteins from Deinococcus radiodurans and Streptomyces coelicolor belonging to Pfam protein family DUF178 (ID: PF02621) have been determined using Selenium-Single-wavelength Anomalous Dispersion (Se-SAD). Based on the structure, we have identified the putative function for this family of protein. CONCLUSION: Unexpectedly, we found that DUF178 Pfam is remarkably similar to Pfam family DUF191 suggesting that the sequence-based classification alone may not be sufficient to classify proteins into Pfam families.
About this Structure
2I6E is a Single protein structure of sequence from Deinococcus radiodurans. Full crystallographic information is available from OCA.
Reference
X-ray structures of two proteins belonging to Pfam DUF178 revealed unexpected structural similarity to the DUF191 Pfam family., Tyagi R, Burley SK, Swaminathan S, BMC Struct Biol. 2007 Oct 1;7:62. PMID:17908300 Page seeded by OCA on Sun May 4 07:07:58 2008
Proteopedia Page Contributors and Editors (what is this?)
- Pages with broken file links
- Deinococcus radiodurans
- Single protein
- Burley, S K.
- Kumaran, D.
- NYSGXRC, New York Structural GenomiX Research Consortium.
- Swaminathan, S.
- Tyagi, R.
- Hypothetical protein,pfam:duf178
- New york structural genomix research consortium
- Nysgxrc,10093b
- Protein structure initiative
- Psi-2
- Structural genomic
- Unknown function
