2ibs: Difference between revisions

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[[Image:2ibs.gif|left|200px]]
[[Image:2ibs.gif|left|200px]]


{{Structure
<!--
|PDB= 2ibs |SIZE=350|CAPTION= <scene name='initialview01'>2ibs</scene>, resolution 2.40&Aring;
The line below this paragraph, containing "STRUCTURE_2ibs", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=2PR:2-AMINO-9-[2-DEOXYRIBOFURANOSYL]-9H-PURINE-5&#39;-MONOPHOSPHATE'>2PR</scene>, <scene name='pdbligand=6MA:N6-METHYL-DEOXY-ADENOSINE-5&#39;-MONOPHOSPHATE'>6MA</scene>, <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=NEA:5&#39;-DEOXY-5&#39;-[2-(AMINO)ETHYLTHIO]ADENOSINE'>NEA</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Site-specific_DNA-methyltransferase_(adenine-specific) Site-specific DNA-methyltransferase (adenine-specific)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.72 2.1.1.72] </span>
or leave the SCENE parameter empty for the default display.
|GENE= taqIM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=271 Thermus aquaticus])
-->
|DOMAIN=
{{STRUCTURE_2ibs| PDB=2ibs  | SCENE= }}  
|RELATEDENTRY=[[1g38|1G38]], [[2adm|2ADM]], [[1aqi|1AQI]], [[1aqj|1AQJ]], [[2ibt|2IBT]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ibs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ibs OCA], [http://www.ebi.ac.uk/pdbsum/2ibs PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ibs RCSB]</span>
}}


'''Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing 2-aminopurine at the target position'''
'''Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing 2-aminopurine at the target position'''
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2-Aminopurine flipped into the active site of the adenine-specific DNA methyltransferase M.TaqI: crystal structures and time-resolved fluorescence., Lenz T, Bonnist EY, Pljevaljcic G, Neely RK, Dryden DT, Scheidig AJ, Jones AC, Weinhold E, J Am Chem Soc. 2007 May 16;129(19):6240-8. Epub 2007 Apr 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17455934 17455934]
2-Aminopurine flipped into the active site of the adenine-specific DNA methyltransferase M.TaqI: crystal structures and time-resolved fluorescence., Lenz T, Bonnist EY, Pljevaljcic G, Neely RK, Dryden DT, Scheidig AJ, Jones AC, Weinhold E, J Am Chem Soc. 2007 May 16;129(19):6240-8. Epub 2007 Apr 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17455934 17455934]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Site-specific DNA-methyltransferase (adenine-specific)]]
[[Category: Thermus aquaticus]]
[[Category: Thermus aquaticus]]
[[Category: Lenz, T.]]
[[Category: Lenz, T.]]
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[[Category: Weinhold, E.]]
[[Category: Weinhold, E.]]
[[Category: 2-aminopurine]]
[[Category: 2-aminopurine]]
[[Category: base flipping]]
[[Category: Base flipping]]
[[Category: dna]]
[[Category: Dna]]
[[Category: dna methyltransferase]]
[[Category: Dna methyltransferase]]
[[Category: nucleotide flipping]]
[[Category: Nucleotide flipping]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:42:09 2008''