2p3a: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
Line 1: Line 1:
[[Image:2p3a.gif|left|200px]]
[[Image:2p3a.gif|left|200px]]


{{Structure
<!--
|PDB= 2p3a |SIZE=350|CAPTION= <scene name='initialview01'>2p3a</scene>, resolution 1.750&Aring;
The line below this paragraph, containing "STRUCTURE_2p3a", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)
|LIGAND= <scene name='pdbligand=3TL:BENZYL+(2S,5S,8S,9R,10R,11S,14S,17S)-8,11-DIBENZYL-9,10-DIHYDROXY-5,14-DIISOPROPYL-3,6,13,16-TETRAOXO-4,7,12,15-TETRAAZAOCTADECANE-2,17-DIYLDICARBAMATE'>3TL</scene>, <scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span>
or leave the SCENE parameter empty for the default display.
|GENE= pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])
-->
|DOMAIN=
{{STRUCTURE_2p3a| PDB=2p3a  | SCENE= }}  
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3a OCA], [http://www.ebi.ac.uk/pdbsum/2p3a PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2p3a RCSB]</span>
}}


'''Crystal Structure of the multi-drug resistant mutant subtype B HIV protease complexed with TL-3 inhibitor'''
'''Crystal Structure of the multi-drug resistant mutant subtype B HIV protease complexed with TL-3 inhibitor'''
Line 19: Line 16:


==About this Structure==
==About this Structure==
2P3A is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3A OCA].  
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3A OCA].  


==Reference==
==Reference==
Structural characterization of B and non-B subtypes of HIV-protease: insights into the natural susceptibility to drug resistance development., Sanches M, Krauchenco S, Martins NH, Gustchina A, Wlodawer A, Polikarpov I, J Mol Biol. 2007 Jun 15;369(4):1029-40. Epub 2007 Mar 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17467738 17467738]
Structural characterization of B and non-B subtypes of HIV-protease: insights into the natural susceptibility to drug resistance development., Sanches M, Krauchenco S, Martins NH, Gustchina A, Wlodawer A, Polikarpov I, J Mol Biol. 2007 Jun 15;369(4):1029-40. Epub 2007 Mar 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17467738 17467738]
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Protein complex]]
[[Category: Gustchina, A.]]
[[Category: Gustchina, A.]]
[[Category: Krauchenco, S.]]
[[Category: Krauchenco, S.]]
Line 32: Line 27:
[[Category: Sanches, M.]]
[[Category: Sanches, M.]]
[[Category: Wlodawer, A.]]
[[Category: Wlodawer, A.]]
[[Category: multi-drug resistant mutant subtype b hiv protease]]
[[Category: Multi-drug resistant mutant subtype b hiv protease]]
[[Category: protease-inhibitor complex]]
[[Category: Protease-inhibitor complex]]
[[Category: tl-3 inhibitor]]
[[Category: Tl-3 inhibitor]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 12:15:10 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:28:21 2008''
Retrieved from "https://proteopedia.org/2p3a"