2pxi: Difference between revisions

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[[Image:2pxi.jpg|left|200px]]
[[Image:2pxi.jpg|left|200px]]


{{Structure
<!--
|PDB= 2pxi |SIZE=350|CAPTION= <scene name='initialview01'>2pxi</scene>, resolution 2.10&Aring;
The line below this paragraph, containing "STRUCTURE_2pxi", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DOC:2&#39;,3&#39;-DIDEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DOC</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=GFH:2&#39;-DEOXY-5&#39;-O-[(R)-{[(R)-[(R)-FLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]GUANOSINE'>GFH</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY=
or leave the SCENE parameter empty for the default display.
|GENE= POLB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
-->
|DOMAIN=
{{STRUCTURE_2pxi| PDB=2pxi  | SCENE= }}  
|RELATEDENTRY=[[2iso|2ISO]], [[2isp|2ISP]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pxi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pxi OCA], [http://www.ebi.ac.uk/pdbsum/2pxi PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pxi RCSB]</span>
}}


'''Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monofluoromethylene triphosphate'''
'''Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monofluoromethylene triphosphate'''
Line 27: Line 24:
[[Category: Pedersen, L C.]]
[[Category: Pedersen, L C.]]
[[Category: Wilson, S H.]]
[[Category: Wilson, S H.]]
[[Category: chiral interaction]]
[[Category: Chiral interaction]]
[[Category: dna polymerase]]
[[Category: Dna polymerase]]
[[Category: lyase]]
[[Category: Lyase]]
[[Category: nucleotidyl transferase]]
[[Category: Nucleotidyl transferase]]
[[Category: stereoselectivity]]
[[Category: Stereoselectivity]]
[[Category: transferase/dna complex]]
[[Category: Transferase/dna complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 13:58:32 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:42:03 2008''

Revision as of 10:58, 4 May 2008

File:2pxi.jpg

Template:STRUCTURE 2pxi

Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monofluoromethylene triphosphate


About this Structure

2PXI is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

(R)-beta,gamma-fluoromethylene-dGTP-DNA ternary complex with DNA polymerase beta., McKenna CE, Kashemirov BA, Upton TG, Batra VK, Goodman MF, Pedersen LC, Beard WA, Wilson SH, J Am Chem Soc. 2007 Dec 19;129(50):15412-3. Epub 2007 Nov 22. PMID:18031037 Page seeded by OCA on Sun May 4 13:58:32 2008

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