366d: Difference between revisions

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[[Image:366d.gif|left|200px]]
[[Image:366d.gif|left|200px]]


{{Structure
<!--
|PDB= 366d |SIZE=350|CAPTION= <scene name='initialview01'>366d</scene>, resolution 1.30&Aring;
The line below this paragraph, containing "STRUCTURE_366d", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=BRU:5-BROMO-2&#39;-DEOXYURIDINE-5&#39;-MONOPHOSPHATE'>BRU</scene>, <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DA6:6-BROMO-9-AMINO-N-ETHYL(DIAMINOMETHYL)ACRIDINE-4-CARBOXAMIDE'>DA6</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY=  
or leave the SCENE parameter empty for the default display.
|GENE=  
-->
|DOMAIN=
{{STRUCTURE_366d| PDB=366d  | SCENE= }}  
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=366d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=366d OCA], [http://www.ebi.ac.uk/pdbsum/366d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=366d RCSB]</span>
}}


'''1.3 A STRUCTURE DETERMINATION OF THE D(CG(5-BRU)ACG)2/6-BROMO-9-AMINO-DACA COMPLEX'''
'''1.3 A STRUCTURE DETERMINATION OF THE D(CG(5-BRU)ACG)2/6-BROMO-9-AMINO-DACA COMPLEX'''
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==About this Structure==
==About this Structure==
366D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=366D OCA].  
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=366D OCA].  


==Reference==
==Reference==
Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution., Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ, J Med Chem. 1999 Feb 25;42(4):536-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10052960 10052960]
Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution., Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ, J Med Chem. 1999 Feb 25;42(4):536-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10052960 10052960]
[[Category: Protein complex]]
[[Category: Adams, A.]]
[[Category: Adams, A.]]
[[Category: Cardin, C J.]]
[[Category: Cardin, C J.]]
Line 26: Line 22:
[[Category: Thorpe, J H.]]
[[Category: Thorpe, J H.]]
[[Category: Todd, A K.]]
[[Category: Todd, A K.]]
[[Category: dna]]
[[Category: Dna]]
[[Category: drug intercalation]]
[[Category: Drug intercalation]]
[[Category: major groove binding]]
[[Category: Major groove binding]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 20:17:32 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:21:51 2008''

Revision as of 17:17, 4 May 2008

File:366d.gif

Template:STRUCTURE 366d

1.3 A STRUCTURE DETERMINATION OF THE D(CG(5-BRU)ACG)2/6-BROMO-9-AMINO-DACA COMPLEX


About this Structure

Full crystallographic information is available from OCA.

Reference

Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution., Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ, J Med Chem. 1999 Feb 25;42(4):536-40. PMID:10052960 Page seeded by OCA on Sun May 4 20:17:32 2008

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