367d: Difference between revisions

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[[Image:367d.gif|left|200px]]
[[Image:367d.gif|left|200px]]


{{Structure
<!--
|PDB= 367d |SIZE=350|CAPTION= <scene name='initialview01'>367d</scene>, resolution 1.200&Aring;
The line below this paragraph, containing "STRUCTURE_367d", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)
|LIGAND= <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DA5:5-BROMO-9-AMINO-N-ETHYL(DIAMINOMETHYL)ACRIDINE-4-CARBOXAMIDE'>DA5</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DU:2&#39;-DEOXYURIDINE-5&#39;-MONOPHOSPHATE'>DU</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY=  
or leave the SCENE parameter empty for the default display.
|GENE=  
-->
|DOMAIN=
{{STRUCTURE_367d| PDB=367d  | SCENE= }}  
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=367d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=367d OCA], [http://www.ebi.ac.uk/pdbsum/367d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=367d RCSB]</span>
}}


'''1.2 A STRUCTURE DETERMINATION OF THE D(CG(5-BRU)ACG)2/5-BROMO-9-AMINO-DACA COMPLEX'''
'''1.2 A STRUCTURE DETERMINATION OF THE D(CG(5-BRU)ACG)2/5-BROMO-9-AMINO-DACA COMPLEX'''
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==About this Structure==
==About this Structure==
367D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=367D OCA].  
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=367D OCA].  


==Reference==
==Reference==
Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution., Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ, J Med Chem. 1999 Feb 25;42(4):536-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10052960 10052960]
Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution., Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ, J Med Chem. 1999 Feb 25;42(4):536-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10052960 10052960]
[[Category: Protein complex]]
[[Category: Adams, A.]]
[[Category: Adams, A.]]
[[Category: Cardin, C J.]]
[[Category: Cardin, C J.]]
Line 26: Line 22:
[[Category: Thorpe, J H.]]
[[Category: Thorpe, J H.]]
[[Category: Todd, A K.]]
[[Category: Todd, A K.]]
[[Category: complexed with drug]]
[[Category: Complexed with drug]]
[[Category: dna]]
[[Category: Dna]]
[[Category: double helix]]
[[Category: Double helix]]
[[Category: modified]]
[[Category: Modified]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 20:17:37 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:21:52 2008''

Revision as of 17:17, 4 May 2008

File:367d.gif

Template:STRUCTURE 367d

1.2 A STRUCTURE DETERMINATION OF THE D(CG(5-BRU)ACG)2/5-BROMO-9-AMINO-DACA COMPLEX


About this Structure

Full crystallographic information is available from OCA.

Reference

Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution., Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ, J Med Chem. 1999 Feb 25;42(4):536-40. PMID:10052960 Page seeded by OCA on Sun May 4 20:17:37 2008

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