4tln: Difference between revisions

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[[Image:4tln.jpg|left|200px]]
[[Image:4tln.jpg|left|200px]]


{{Structure
<!--
|PDB= 4tln |SIZE=350|CAPTION= <scene name='initialview01'>4tln</scene>, resolution 2.3&Aring;
The line below this paragraph, containing "STRUCTURE_4tln", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=LNO:L-LEUCYL-HYDROXYLAMINE'>LNO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] </span>
or leave the SCENE parameter empty for the default display.
|GENE=  
-->
|DOMAIN=
{{STRUCTURE_4tln| PDB=4tln  | SCENE= }}  
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tln FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tln OCA], [http://www.ebi.ac.uk/pdbsum/4tln PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=4tln RCSB]</span>
}}


'''BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS'''
'''BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS'''
Line 25: Line 22:
[[Category: Holmes, M A.]]
[[Category: Holmes, M A.]]
[[Category: Matthews, B W.]]
[[Category: Matthews, B W.]]
[[Category: hydrolase (metalloproteinase)]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 22:30:10 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:40:18 2008''

Revision as of 19:30, 4 May 2008

File:4tln.jpg

Template:STRUCTURE 4tln

BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS


About this Structure

4TLN is a Single protein structure of sequence from Bacillus thermoproteolyticus. Full crystallographic information is available from OCA.

Reference

Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis., Holmes MA, Matthews BW, Biochemistry. 1981 Nov 24;20(24):6912-20. PMID:7317361 Page seeded by OCA on Sun May 4 22:30:10 2008

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