1bbt: Difference between revisions

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[[Image:1bbt.gif|left|200px]]
[[Image:1bbt.png|left|200px]]


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==Overview==
{{ABSTRACT_8382928}}
The structure of foot-and-mouth disease virus (FMDV) strain O1 BFS 1860 has been determined to 2.9 A resolution using the molecular-replacement method [Acharya, Fry, Stuart, Fox, Rowlands &amp; Brown (1989). Nature (London), 337, 709-716]. Crystals of the virus with average dimensions 0.12 x 0.06 x 0.12 mm belong to space group I23, a = 345 A with 1/12 of the icosahedral particle per asymmetric unit giving fivefold noncrystallographic redundancy. Oscillation diffraction photographs were collected at the SERC Synchrotron Radiation Source at Daresbury in accordance with strict disease security regulations. The ambiguity in particle orientation was resolved using a self-rotation function and starting estimates of the phases to 8 A were derived from the known structures of two picornaviruses similarly oriented in the I23 unit cell. The phases were refined and extended using iterative averaging and solvent flattening with the implementation of a simple automatic envelope-determination procedure to increase the phasing power available.


==About this Structure==
==About this Structure==
1BBT is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Foot-and-mouth_disease_virus Foot-and-mouth disease virus]. The following page contains interesting information on the relation of 1BBT with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb20_1.html Poliovirus and Rhinovirus]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBT OCA].  
1BBT is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Foot-and-mouth_disease_virus Foot-and-mouth disease virus]. The following page contains interesting information on the relation of 1BBT with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb20_1.html Poliovirus and Rhinovirus]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBT OCA].  
==Reference==
Methods used in the structure determination of foot-and-mouth disease virus., Fry E, Acharya R, Stuart D, Acta Crystallogr A. 1993 Jan 1;49 ( Pt 1):45-55. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8382928 8382928]
[[Category: Foot-and-mouth disease virus]]
[[Category: Foot-and-mouth disease virus]]
[[Category: Poliovirus and Rhinovirus]]
[[Category: Poliovirus and Rhinovirus]]
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[[Category: Icosahedral virus]]
[[Category: Icosahedral virus]]
[[Category: Virus]]
[[Category: Virus]]
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