1a4v: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
Line 1: Line 1:
[[Image:1a4v.gif|left|200px]]
{{Seed}}
[[Image:1a4v.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1a4v|  PDB=1a4v  |  SCENE=  }}  
{{STRUCTURE_1a4v|  PDB=1a4v  |  SCENE=  }}  


'''ALPHA-LACTALBUMIN'''
===ALPHA-LACTALBUMIN===




==Overview==
<!--
The high-resolution X-ray crystal structure of human alpha-lactalbumin (at 1.8 A) in the presence of an elevated level of calcium reveals a new secondary calcium binding site, 7.9 A away from the primary calcium binding site known in all alpha-lactalbumin structures so far. The new calcium binding site is different from the zinc and sulfate binding sites [Ren, J., et al. (1993) J. Biol. Chem. 268, 19292-19298] but shares common features with the manganese binding site as described by Gerkin [Gerkin, T. A. (1984) Biochemistry 23, 4688-4697]. The proximity of the manganese and calcium binding region and the location of the functional site on one side of the charged surface of the alpha-lactalbumin molecule suggest that these binding sites might play a role in the formation of the lactose synthase complex.
The line below this paragraph, {{ABSTRACT_PUBMED_9537992}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 9537992 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_9537992}}


==About this Structure==
==About this Structure==
Line 28: Line 32:
[[Category: Calcium binding]]
[[Category: Calcium binding]]
[[Category: Lactose synthase]]
[[Category: Lactose synthase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 09:48:53 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 16:07:48 2008''

Revision as of 13:07, 30 June 2008

File:1a4v.png


Drag the structure with the mouse to rotate
1a4v, resolution 1.80Å (default scene)
Ligands: CA
Activity: Lactose synthase, with EC number 2.4.1.22
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



ALPHA-LACTALBUMIN

Template:ABSTRACT PUBMED 9537992

About this Structure

1A4V is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Structural evidence for the presence of a secondary calcium binding site in human alpha-lactalbumin., Chandra N, Brew K, Acharya KR, Biochemistry. 1998 Apr 7;37(14):4767-72. PMID:9537992

Page seeded by OCA on Mon Jun 30 16:07:48 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=1a4v&oldid=570983"