1a6s: Difference between revisions

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[[Image:1a6s.~~gif~~|left|200px]]

[[Image:1a6s.png|left|200px]]

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~~'''~~M-DOMAIN FROM GAG POLYPROTEIN OF ROUS SARCOMA VIRUS, NMR, 20 STRUCTURES~~'''~~

===M-DOMAIN FROM GAG POLYPROTEIN OF ROUS SARCOMA VIRUS, NMR, 20 STRUCTURES===

~~==Overview==~~

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A biologically active construct of the retroviral M domain from the avian Rous sarcoma virus is defined and its solution structure described. This M domain is fully active in budding and infectivity without myristylation. In spite of a sequence homology level that suggests no relationship among M domains and the family of matrix proteins in mammalian retroviruses, the ~~conserved structural elements of a central core allow an M domain sequence motif~~ to ~~be described for all retroviruses~~. ~~The surface of the M domain has a highly clustered positive patch comprised of sequentially distant residues~~. ~~An analysis of the backbone dynamics, incorporating rotational anisotropy~~, is ~~used to estimate~~ the ~~thermodynamics of proposed domain oligomerization~~.

The line below this paragraph, {{ABSTRACT_PUBMED_9642071}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 9642071 is the PubMed ID number.

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==About this Structure==

1A6S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6S OCA].

1A6S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6S OCA].

==Reference==

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[[Category: Membrane binding]]

[[Category: Virus structure]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Fri May 2 09~~:54:03 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 16:15:58 2008''

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-[[Image:1a6s.gif|left|200px]]
+{{Seed}}
+[[Image:1a6s.png|left|200px]]
 <!--
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 {{STRUCTURE_1a6s|  PDB=1a6s  |  SCENE=  }}
-'''M-DOMAIN FROM GAG POLYPROTEIN OF ROUS SARCOMA VIRUS, NMR, 20 STRUCTURES'''
+===M-DOMAIN FROM GAG POLYPROTEIN OF ROUS SARCOMA VIRUS, NMR, 20 STRUCTURES===
-==Overview==
+<!--
-A biologically active construct of the retroviral M domain from the avian Rous sarcoma virus is defined and its solution structure described. This M domain is fully active in budding and infectivity without myristylation. In spite of a sequence homology level that suggests no relationship among M domains and the family of matrix proteins in mammalian retroviruses, the conserved structural elements of a central core allow an M domain sequence motif to be described for all retroviruses. The surface of the M domain has a highly clustered positive patch comprised of sequentially distant residues. An analysis of the backbone dynamics, incorporating rotational anisotropy, is used to estimate the thermodynamics of proposed domain oligomerization.
+The line below this paragraph, {{ABSTRACT_PUBMED_9642071}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 9642071 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_9642071}}
 ==About this Structure==
-A6S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6S OCA].
+A6S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6S OCA].
 ==Reference==
@@ Line 35: / Line 39: @@
 [[Category: Membrane binding]]
 [[Category: Virus structure]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 09:54:03 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 16:15:58 2008''