1bn9: Difference between revisions

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[[Image:1bn9.gif|left|200px]]
{{Seed}}
[[Image:1bn9.png|left|200px]]


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{{STRUCTURE_1bn9|  PDB=1bn9  |  SCENE=  }}  
{{STRUCTURE_1bn9|  PDB=1bn9  |  SCENE=  }}  


'''RESPONSE ELEMENT OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB BETA'''
===RESPONSE ELEMENT OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB BETA===




==Overview==
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Rev-erb beta is an orphan receptor that binds as a homodimer or as a monomer to DNA. The solution structure of the non-palindromic 15 bp DNA duplex d(TAGAATGTAGGTCAG), the response element of Rev-erb beta for monomeric binding, was determined by 1H and 31P NMR, energy minimization with NMR-derived restraints for distances and NOE back-calculation methods. The refined final structures have the typical overall features of B-type DNA. However, titration of this 15 bp duplex with ReDBD, the DNA binding domain of Rev-erb beta, showed large shifts of imino protons and 31P signals, suggesting major conformational changes.
The line below this paragraph, {{ABSTRACT_PUBMED_11018291}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11018291 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11018291}}


==About this Structure==
==About this Structure==
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BN9 OCA].  
Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BN9 OCA].  


==Reference==
==Reference==
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[[Category: Orphan nuclear receptor]]
[[Category: Orphan nuclear receptor]]
[[Category: Response element]]
[[Category: Response element]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 11:43:35 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 19:24:51 2008''

Revision as of 16:24, 30 June 2008

File:1bn9.png

Template:STRUCTURE 1bn9

RESPONSE ELEMENT OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB BETA

Template:ABSTRACT PUBMED 11018291

About this Structure

Full experimental information is available from OCA.

Reference

Solution structure of the orphan nuclear receptor rev-erb beta response element by 1H, 31P NMR and molecular simulation*., Castagne C, Terenzi H, Zakin MM, Delepierre M, Biochimie. 2000 Aug;82(8):739-48. PMID:11018291

Page seeded by OCA on Mon Jun 30 19:24:51 2008

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