1cwi: Difference between revisions

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[[Image:1cwi.gif|left|200px]]
{{Seed}}
[[Image:1cwi.png|left|200px]]


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{{STRUCTURE_1cwi|  PDB=1cwi  |  SCENE=  }}  
{{STRUCTURE_1cwi|  PDB=1cwi  |  SCENE=  }}  


'''HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL 3-(N-METHYL)-D-ALANINE CYCLOSPORIN'''
===HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL 3-(N-METHYL)-D-ALANINE CYCLOSPORIN===




==Overview==
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Eight new X-ray structures of different cyclophilin A/cyclosporin-derivative complexes are presented. These structures, combined with the existing three published cyclosporin complexes, provide a useful structural database for the analysis of protein-ligand interactions. The effect of small chemical differences on protein-ligand hydrogen-bonding, van der Waals interactions and water structure is presented.
The line below this paragraph, {{ABSTRACT_PUBMED_9769216}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_9769216}}


==About this Structure==
==About this Structure==
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[[Category: Taylor, P.]]
[[Category: Taylor, P.]]
[[Category: Walkinshaw, M D.]]
[[Category: Walkinshaw, M D.]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 13:11:11 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 21:37:53 2008''