1d65: Difference between revisions

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[[Image:1d65.gif|left|200px]]
{{Seed}}
[[Image:1d65.png|left|200px]]


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{{STRUCTURE_1d65|  PDB=1d65  |  SCENE=  }}  
{{STRUCTURE_1d65|  PDB=1d65  |  SCENE=  }}  


'''MOLECULAR STRUCTURE OF THE B-DNA DODECAMER D(CGCAAATTTGCG)2; AN EXAMINATION OF PROPELLER TWIST AND MINOR-GROOVE WATER STRUCTURE AT 2.2 ANGSTROMS RESOLUTION'''
===MOLECULAR STRUCTURE OF THE B-DNA DODECAMER D(CGCAAATTTGCG)2; AN EXAMINATION OF PROPELLER TWIST AND MINOR-GROOVE WATER STRUCTURE AT 2.2 ANGSTROMS RESOLUTION===




==Overview==
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The crystal structure of the dodecanucleotide duplex d(CGCAAATTTGCG)2 has been solved to 2.2 A resolution and refined to an R-factor of 18.1% with the inclusion of 71 water molecules. The structure shows propeller twists of up to -20 degrees for the A.T base-pairs, although there is probably only one (weak) three-centre hydrogen bond in the six base-pair AT narrow minor-groove region. An extensive ribbon of hydration has been located in this groove that has features distinctive from the classic "spine of hydration". Solvation around phosphate groups is described, with several instances of water molecules bridging between phosphates.
The line below this paragraph, {{ABSTRACT_PUBMED_1518049}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 1518049 is the PubMed ID number.
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{{ABSTRACT_PUBMED_1518049}}


==About this Structure==
==About this Structure==
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[[Category: B-dna]]
[[Category: B-dna]]
[[Category: Double helix]]
[[Category: Double helix]]
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