1da2: Difference between revisions

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[[Image:1da2.~~gif~~|left|200px]]

[[Image:1da2.png|left|200px]]

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~~'''~~MOLECULAR AND CRYSTAL STRUCTURE OF D(CGCGMO4CG): N4-METHOXYCYTOSINE/GUANINE BASE-PAIRS IN Z-DNA~~'''~~

===MOLECULAR AND CRYSTAL STRUCTURE OF D(CGCGMO4CG): N4-METHOXYCYTOSINE/GUANINE BASE-PAIRS IN Z-DNA===

~~==Overview==~~

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The ~~base analogue N4-methoxycytosine (mo4C) is ambivalent in its hydrogen-bonding potential~~, ~~since it forms stable base-pairs with both adenine and guanine in oligomer duplexes. To investigate~~ the ~~base-pair geometry,~~ the ~~structure of d~~(CGCGmo4CG) has been determined by single-crystal X-ray diffraction techniques. The d(CGCGmo4CG)2 crystallized in a left-handed double helical structure (Z-type). Refinement using 2559 reflections between 10 and 1.7 A converged with a final R = 0.181 (Rw = 0.~~130) including 68 solvent molecules~~. ~~The orthorhombic crystals are in the space group P2(1)2(1)2(1~~), ~~with cell dimensions a = 18.17 A, b = 30.36 A, c = 43.93 A. The mo4C.G base-pair~~ is ~~of the wobble type, with mo4C in the imino form, and the methoxy group in~~ the ~~syn configuration~~.

The line below this paragraph, {{ABSTRACT_PUBMED_2258939}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 2258939 is the PubMed ID number.

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==About this Structure==

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[[Category: Modified]]

[[Category: Z-dna]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Fri May 2 13~~:37:10 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 22:44:00 2008''

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-[[Image:1da2.gif|left|200px]]
+{{Seed}}
+[[Image:1da2.png|left|200px]]
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 {{STRUCTURE_1da2|  PDB=1da2  |  SCENE=  }}
-'''MOLECULAR AND CRYSTAL STRUCTURE OF D(CGCGMO4CG): N4-METHOXYCYTOSINE/GUANINE BASE-PAIRS IN Z-DNA'''
+===MOLECULAR AND CRYSTAL STRUCTURE OF D(CGCGMO4CG): N4-METHOXYCYTOSINE/GUANINE BASE-PAIRS IN Z-DNA===
-==Overview==
+<!--
-The base analogue N4-methoxycytosine (mo4C) is ambivalent in its hydrogen-bonding potential, since it forms stable base-pairs with both adenine and guanine in oligomer duplexes. To investigate the base-pair geometry, the structure of d(CGCGmo4CG) has been determined by single-crystal X-ray diffraction techniques. The d(CGCGmo4CG)2 crystallized in a left-handed double helical structure (Z-type). Refinement using 2559 reflections between 10 and 1.7 A converged with a final R = 0.181 (Rw = 0.130) including 68 solvent molecules. The orthorhombic crystals are in the space group P2(1)2(1)2(1), with cell dimensions a = 18.17 A, b = 30.36 A, c = 43.93 A. The mo4C.G base-pair is of the wobble type, with mo4C in the imino form, and the methoxy group in the syn configuration.
+The line below this paragraph, {{ABSTRACT_PUBMED_2258939}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 2258939 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_2258939}}
 ==About this Structure==
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 [[Category: Modified]]
 [[Category: Z-dna]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 13:37:10 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 22:44:00 2008''