1fml: Difference between revisions

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{{Seed}}
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{{STRUCTURE_1fml|  PDB=1fml  |  SCENE=  }}  
{{STRUCTURE_1fml|  PDB=1fml  |  SCENE=  }}  


'''CRYSTAL STRUCTURE OF RETINOL DEHYDRATASE IN A COMPLEX WITH RETINOL AND PAP'''
===CRYSTAL STRUCTURE OF RETINOL DEHYDRATASE IN A COMPLEX WITH RETINOL AND PAP===




==Overview==
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We report here the crystal structure of retinol dehydratase, an enzyme that catalyzes the synthesis of anhydroretinol. The enzyme is a member of the sulfotransferase superfamily and its crystal structure reveals the insertion of a helical lid into a canonical sulfotransferase fold. Site-directed mutations demonstrate that this inserted lid is necessary for anhydroretinol production but not for sulfonation; thus, insertion of a helical lid can convert a sulfotransferase into a dehydratase.
The line below this paragraph, {{ABSTRACT_PUBMED_11323722}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_11323722}}


==About this Structure==
==About this Structure==
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[[Category: Retinol]]
[[Category: Retinol]]
[[Category: Sulfotransferase]]
[[Category: Sulfotransferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 16:30:32 2008''
 
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