1glo: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
Line 1: Line 1:
[[Image:1glo.jpg|left|200px]]
{{Seed}}
[[Image:1glo.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1glo|  PDB=1glo  |  SCENE=  }}  
{{STRUCTURE_1glo|  PDB=1glo  |  SCENE=  }}  


'''CRYSTAL STRUCTURE OF CYS25SER MUTANT OF HUMAN CATHEPSIN S'''
===CRYSTAL STRUCTURE OF CYS25SER MUTANT OF HUMAN CATHEPSIN S===




==Overview==
<!--
Cathepsin S (EC 3.4.22.27), a cysteine proteinase of the papain superfamily, plays a critical role in the generation of a major histocompatibility complex (MHC) class II restricted T-cell response by antigen-presenting cells. Therefore, selective inhibition of this enzyme may be useful in modulating class II restricted T-cell responses in immune-related disorders such as rheumatoid arthritis, multiple sclerosis and extrinsic asthma. The three-dimensional structure at 2.2 A resolution of the active-site Cys25--&gt;Ser mutant presented here in an unliganded state provides further insight useful for the design of selective enzyme inhibitors.
The line below this paragraph, {{ABSTRACT_PUBMED_11856830}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11856830 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_11856830}}


==About this Structure==
==About this Structure==
Line 35: Line 39:
[[Category: Proteinase]]
[[Category: Proteinase]]
[[Category: Thiol protea]]
[[Category: Thiol protea]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 17:43:48 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 05:29:32 2008''
Retrieved from "https://proteopedia.org/1glo"