1gvg: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
Line 1: Line 1:
[[Image:1gvg.jpg|left|200px]]
{{Seed}}
[[Image:1gvg.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1gvg|  PDB=1gvg  |  SCENE=  }}  
{{STRUCTURE_1gvg|  PDB=1gvg  |  SCENE=  }}  


'''CRYSTAL STRUCTURE OF CLAVAMINATE SYNTHASE WITH NITRIC OXIDE'''
===CRYSTAL STRUCTURE OF CLAVAMINATE SYNTHASE WITH NITRIC OXIDE===




==Overview==
<!--
Clavaminate synthase (CAS), a 2-oxoglutarate (2OG) dependent dioxygenase, catalyses three steps in the biosynthesis of clavulanic acid. Crystals of CAS complexed with Fe(II), 2OG and deoxyguanidinoproclavaminate were exposed to nitric oxide (NO) acting as a dioxygen analogue. Prior to exposure with NO, the active site Fe(II) is octahedrally coordinated by a water molecule, the 2-oxo and 1-carboxylate groups of 2OG, and the side-chains of an aspartyl and two histidinyl residues. NO binds to the position previously occupied by the 2OG 1-carboxylate concomitant with rearrangement of the latter to the position previously occupied by the displaced water.
The line below this paragraph, {{ABSTRACT_PUBMED_12062399}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 12062399 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_12062399}}


==About this Structure==
==About this Structure==
Line 35: Line 39:
[[Category: Oxygenase]]
[[Category: Oxygenase]]
[[Category: Trifunctional enzyme]]
[[Category: Trifunctional enzyme]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 18:03:35 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 06:08:50 2008''
Retrieved from "https://proteopedia.org/1gvg"