1hdm: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
Line 1: Line 1:
[[Image:1hdm.jpg|left|200px]]
{{Seed}}
[[Image:1hdm.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1hdm|  PDB=1hdm  |  SCENE=  }}  
{{STRUCTURE_1hdm|  PDB=1hdm  |  SCENE=  }}  


'''HISTOCOMPATIBILITY ANTIGEN HLA-DM'''
===HISTOCOMPATIBILITY ANTIGEN HLA-DM===




==Overview==
<!--
The three-dimensional structure of the soluble ecto-domain of HLA-DM has been determined to 2.5 A resolution by X-ray crystallography. HLA-DM has both peptide exchange activity and acts as a chaperone to peptide-free class II MHC molecules. As predicted, the structure is similar to that of classical class II MHC molecules except that the peptide-binding site is altered to an almost fully closed groove. An unusual cavity is found at the center of the region that binds peptides in class II MHC molecules, and a tryptophanrich lateral surface is identified that is a candidate both for binding to HLA-DR, to effect catalysis, and to HLA-DO, an inhibitor.
The line below this paragraph, {{ABSTRACT_PUBMED_9768757}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 9768757 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_9768757}}


==About this Structure==
==About this Structure==
Line 25: Line 29:
[[Category: Wiley, D C.]]
[[Category: Wiley, D C.]]
[[Category: Histocompatibility protein]]
[[Category: Histocompatibility protein]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 18:44:14 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 08:02:27 2008''
Retrieved from "https://proteopedia.org/1hdm"