1ide: Difference between revisions

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[[Image:1ide.jpg|left|200px]]
{{Seed}}
[[Image:1ide.png|left|200px]]


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{{STRUCTURE_1ide|  PDB=1ide  |  SCENE=  }}  
{{STRUCTURE_1ide|  PDB=1ide  |  SCENE=  }}  


'''ISOCITRATE DEHYDROGENASE Y160F MUTANT STEADY-STATE INTERMEDIATE COMPLEX (LAUE DETERMINATION)'''
===ISOCITRATE DEHYDROGENASE Y160F MUTANT STEADY-STATE INTERMEDIATE COMPLEX (LAUE DETERMINATION)===




==Overview==
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Site-directed mutagenesis and Laue diffraction data to 2.5 A resolution were used to solve the structures of two sequential intermediates formed during the catalytic actions of isocitrate dehydrogenase. Both intermediates are distinct from the enzyme-substrate and enzyme-product complexes. Mutation of key catalytic residues changed the rate determining steps so that protein and substrate intermediates within the overall reaction pathway could be visualized.
The line below this paragraph, {{ABSTRACT_PUBMED_7761851}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_7761851}}


==About this Structure==
==About this Structure==
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[[Category: Stoddard, B L.]]
[[Category: Stoddard, B L.]]
[[Category: Sweet, R M.]]
[[Category: Sweet, R M.]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 19:52:24 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 10:47:49 2008''