1jcu: Difference between revisions

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[[Image:1jcu.~~gif~~|left|200px]]

[[Image:1jcu.png|left|200px]]

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~~'''~~Solution Structure of MTH1692 Protein from Methanobacterium thermoautotrophicum~~'''~~

===Solution Structure of MTH1692 Protein from Methanobacterium thermoautotrophicum===

~~==Overview==~~

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The ~~influx of genomic sequence information has led~~ to the ~~concept of structural proteomics, the determination of protein structures~~ on ~~a genome-wide scale~~. ~~Here we describe an approach to structural proteomics of small proteins using NMR spectroscopy~~. ~~Over 500 small proteins from several organisms were cloned~~, expressed, purified, and evaluated by NMR. Although there was variability among proteomes, overall 20% of these proteins were found to be readily amenable to NMR structure determination. NMR sample preparation was centralized in one facility, and a distributive approach was used for NMR data collection and analysis. Twelve structures are reported here as part of this approach, which allowed us to infer putative functions for several conserved hypothetical proteins.

The line below this paragraph, {{ABSTRACT_PUBMED_11854485}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 11854485 is the PubMed ID number.

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==About this Structure==

1JCU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JCU OCA].

1JCU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JCU OCA].

==Reference==

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[[Category: Mixed alpha-beta structure]]

[[Category: Structural genomic]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Fri May~~ ~~2 21~~:04:04 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 20:02:36 2008''

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-[[Image:1jcu.gif|left|200px]]
+{{Seed}}
+[[Image:1jcu.png|left|200px]]
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 {{STRUCTURE_1jcu|  PDB=1jcu  |  SCENE=  }}
-'''Solution Structure of MTH1692 Protein from Methanobacterium thermoautotrophicum'''
+===Solution Structure of MTH1692 Protein from Methanobacterium thermoautotrophicum===
-==Overview==
+<!--
-The influx of genomic sequence information has led to the concept of structural proteomics, the determination of protein structures on a genome-wide scale. Here we describe an approach to structural proteomics of small proteins using NMR spectroscopy. Over 500 small proteins from several organisms were cloned, expressed, purified, and evaluated by NMR. Although there was variability among proteomes, overall 20% of these proteins were found to be readily amenable to NMR structure determination. NMR sample preparation was centralized in one facility, and a distributive approach was used for NMR data collection and analysis. Twelve structures are reported here as part of this approach, which allowed us to infer putative functions for several conserved hypothetical proteins.
+The line below this paragraph, {{ABSTRACT_PUBMED_11854485}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 11854485 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_11854485}}
 ==About this Structure==
-JCU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JCU OCA].
+JCU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JCU OCA].
 ==Reference==
@@ Line 27: / Line 31: @@
 [[Category: Mixed alpha-beta structure]]
 [[Category: Structural genomic]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 21:04:04 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 20:02:36 2008''