1jgp: Difference between revisions

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[[Image:1jgp.gif|left|200px]]
{{Seed}}
[[Image:1jgp.png|left|200px]]


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{{STRUCTURE_1jgp|  PDB=1jgp  |  SCENE=  }}  
{{STRUCTURE_1jgp|  PDB=1jgp  |  SCENE=  }}  


'''The Path of Messenger RNA Through the Ribosome. THIS FILE, 1JGP, CONTAINS THE 30S RIBOSOME SUBUNIT, THREE TRNA, AND MRNA MOLECULES. 50S RIBOSOME SUBUNIT IS IN THE FILE 1GIY'''
===The Path of Messenger RNA Through the Ribosome. THIS FILE, 1JGP, CONTAINS THE 30S RIBOSOME SUBUNIT, THREE TRNA, AND MRNA MOLECULES. 50S RIBOSOME SUBUNIT IS IN THE FILE 1GIY===




==Overview==
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Using X-ray crystallography, we have directly observed the path of mRNA in the 70S ribosome in Fourier difference maps at 7 A resolution. About 30 nucleotides of the mRNA are wrapped in a groove that encircles the neck of the 30S subunit. The Shine-Dalgarno helix is bound in a large cleft between the head and the back of the platform. At the interface, only about eight nucleotides (-1 to +7), centered on the junction between the A and P codons, are exposed, and bond almost exclusively to 16S rRNA. The mRNA enters the ribosome around position +13 to +15, the location of downstream pseudoknots that stimulate -1 translational frame shifting.
The line below this paragraph, {{ABSTRACT_PUBMED_11511350}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11511350 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11511350}}


==About this Structure==
==About this Structure==
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[[Category: Protein synthesis]]
[[Category: Protein synthesis]]
[[Category: Ribosome assembly]]
[[Category: Ribosome assembly]]
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