1ji5: Difference between revisions

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[[Image:1ji5.jpg|left|200px]]
{{Seed}}
[[Image:1ji5.png|left|200px]]


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{{STRUCTURE_1ji5|  PDB=1ji5  |  SCENE=  }}  
{{STRUCTURE_1ji5|  PDB=1ji5  |  SCENE=  }}  


'''Dlp-1 from bacillus anthracis'''
===Dlp-1 from bacillus anthracis===




==Overview==
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Bacillus anthracis is currently under intense investigation due to its primary importance as a human pathogen. Particularly important is the development of novel anti-anthrax vaccines, devoid of the current side effects. A novel class of immunogenic bacterial proteins consists of dodecamers homologous to the DNA-binding protein of Escherichia coli (Dps). Two Dps homologous genes are present in the B. anthracis genome. The crystal structures of these two proteins (Dlp-1 and Dlp-2) have been determined and are presented here. They are sphere-like proteins with an internal cavity. We also show that they act as ferritins and are thus involved in iron uptake and regulation, a fundamental function during bacterial growth.
The line below this paragraph, {{ABSTRACT_PUBMED_11836250}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_11836250}}


==About this Structure==
==About this Structure==
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[[Category: Dodecamer]]
[[Category: Dodecamer]]
[[Category: Four-helix bundle]]
[[Category: Four-helix bundle]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 21:15:06 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 20:16:56 2008''
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