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[[Image:1jj2.jpg|left|200px]]
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[[Image:1jj2.png|left|200px]]


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{{STRUCTURE_1jj2|  PDB=1jj2  |  SCENE=  }}  
{{STRUCTURE_1jj2|  PDB=1jj2  |  SCENE=  }}  


'''Fully Refined Crystal Structure of the Haloarcula marismortui Large Ribosomal Subunit at 2.4 Angstrom Resolution'''
===Fully Refined Crystal Structure of the Haloarcula marismortui Large Ribosomal Subunit at 2.4 Angstrom Resolution===




==Overview==
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Analysis of the Haloarcula marismortui large ribosomal subunit has revealed a common RNA structure that we call the kink-turn, or K-turn. The six K-turns in H.marismortui 23S rRNA superimpose with an r.m.s.d. of 1.7 A. There are two K-turns in the structure of Thermus thermophilus 16S rRNA, and the structures of U4 snRNA and L30e mRNA fragments form K-turns. The structure has a kink in the phosphodiester backbone that causes a sharp turn in the RNA helix. Its asymmetric internal loop is flanked by C-G base pairs on one side and sheared G-A base pairs on the other, with an A-minor interaction between these two helical stems. A derived consensus secondary structure for the K-turn includes 10 consensus nucleotides out of 15, and predicts its presence in the 5'-UTR of L10 mRNA, helix 78 in Escherichia coli 23S rRNA and human RNase MRP. Five K-turns in 23S rRNA interact with nine proteins. While the observed K-turns interact with proteins of unrelated structures in different ways, they interact with L7Ae and two homologous proteins in the same way.
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{{ABSTRACT_PUBMED_11483524}}


==About this Structure==
==About this Structure==
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[[Category: Ribosome assembly]]
[[Category: Ribosome assembly]]
[[Category: Rna-rna]]
[[Category: Rna-rna]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 21:17:08 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 20:19:32 2008''

Revision as of 17:19, 1 July 2008

File:1jj2.png

Template:STRUCTURE 1jj2

Fully Refined Crystal Structure of the Haloarcula marismortui Large Ribosomal Subunit at 2.4 Angstrom Resolution

Template:ABSTRACT PUBMED 11483524

About this Structure

1JJ2 is a Protein complex structure of sequences from Haloarcula marismortui. Full crystallographic information is available from OCA.

Reference

The kink-turn: a new RNA secondary structure motif., Klein DJ, Schmeing TM, Moore PB, Steitz TA, EMBO J. 2001 Aug 1;20(15):4214-21. PMID:11483524

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