1k6d: Difference between revisions

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[[Image:1k6d.gif|left|200px]]
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{{STRUCTURE_1k6d|  PDB=1k6d  |  SCENE=  }}  
{{STRUCTURE_1k6d|  PDB=1k6d  |  SCENE=  }}  


'''CRYSTAL STRUCTURE OF ACETATE COA-TRANSFERASE ALPHA SUBUNIT'''
===CRYSTAL STRUCTURE OF ACETATE COA-TRANSFERASE ALPHA SUBUNIT===




==Overview==
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The automation of protein structure determination is an essential component for high-throughput structural analysis in protein X-ray crystallography and is a key element in structural genomics. This highly challenging undertaking relies at present on the availability of high-quality native and derivatized protein crystals diffracting to high or moderate resolution, respectively. Obtaining such crystals often requires significant effort. The present study demonstrates that phases obtained at low resolution (&gt;3.0 A) from crystals of SeMet-labeled protein can be successfully used for automated structure determination. The crystal structure of acetate CoA-transferase alpha-subunit was solved using 3.4 A multi-wavelength anomalous dispersion data collected from a crystal containing SeMet-substituted protein and 1.9 A data collected from a native protein crystal.
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{{ABSTRACT_PUBMED_12454473}}


==About this Structure==
==About this Structure==
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[[Category: Psi]]
[[Category: Psi]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 09:50:56 2008''

Revision as of 06:50, 2 July 2008

File:1k6d.png

Template:STRUCTURE 1k6d

CRYSTAL STRUCTURE OF ACETATE COA-TRANSFERASE ALPHA SUBUNIT

Template:ABSTRACT PUBMED 12454473

About this Structure

1K6D is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Autotracing of Escherichia coli acetate CoA-transferase alpha-subunit structure using 3.4 A MAD and 1.9 A native data., Korolev S, Koroleva O, Petterson K, Gu M, Collart F, Dementieva I, Joachimiak A, Acta Crystallogr D Biol Crystallogr. 2002 Dec;58(Pt 12):2116-21. Epub 2002, Nov 23. PMID:12454473

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