1kct: Difference between revisions

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[[Image:1kct.jpg|left|200px]]
{{Seed}}
[[Image:1kct.png|left|200px]]


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{{STRUCTURE_1kct|  PDB=1kct  |  SCENE=  }}  
{{STRUCTURE_1kct|  PDB=1kct  |  SCENE=  }}  


'''ALPHA1-ANTITRYPSIN'''
===ALPHA1-ANTITRYPSIN===




==Overview==
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The crystal structure of a recombinant human alpha 1-antitrypsin, in the uncleaved and uncomplexed state, has been determined by X-ray crystallographic methods and refined to an R-factor of 18.4% for 8.0-3.46 A data with good stereochemistry. This structure provides the first view at the inhibitory loop and the central beta-sheet A of the uncleaved alpha 1-antitrypsin. The reactive loop takes a distorted helical conformation and no pre-insertion of two residues in the reactive loop into the beta-sheet A is observed. The present structure is largely in agreement with the model predicted by Engh, Wright, and Huber [Prot. Eng. 3 (1990) 469-477].
The line below this paragraph, {{ABSTRACT_PUBMED_8543039}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 8543039 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8543039}}


==About this Structure==
==About this Structure==
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[[Category: Serine protease inhibitor]]
[[Category: Serine protease inhibitor]]
[[Category: Serpin]]
[[Category: Serpin]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 22:35:02 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 10:08:33 2008''
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