1ken: Difference between revisions

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Bots, Bureaucrats, journal, Administrators
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[[Image:1ken.gif|left|200px]]
{{Seed}}
[[Image:1ken.png|left|200px]]


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{{STRUCTURE_1ken|  PDB=1ken  |  SCENE=  }}  
{{STRUCTURE_1ken|  PDB=1ken  |  SCENE=  }}  


'''INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH AN ANTIBODY THAT PREVENTS THE HEMAGGLUTININ LOW PH FUSOGENIC TRANSITION'''
===INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH AN ANTIBODY THAT PREVENTS THE HEMAGGLUTININ LOW PH FUSOGENIC TRANSITION===




==Overview==
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We have determined the structure of a complex of influenza hemagglutinin (HA) with an antibody that binds simultaneously to the membrane-distal domains of two HA monomers, effectively cross-linking them. The antibody prevents the low pH structural transition of HA that is required for its membrane fusion activity, providing evidence that a rearrangement of HA membrane-distal domains is an essential component of the transition.
The line below this paragraph, {{ABSTRACT_PUBMED_11886266}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11886266 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11886266}}


==About this Structure==
==About this Structure==
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[[Category: Glycoprotein]]
[[Category: Glycoprotein]]
[[Category: Hemagglutinin]]
[[Category: Hemagglutinin]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 22:38:56 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 10:13:32 2008''
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