1l2n: Difference between revisions

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[[Image:1l2n.~~jpg~~|left|200px]]

[[Image:1l2n.png|left|200px]]

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~~'''~~Smt3 Solution Structure~~'''~~

===Smt3 Solution Structure===

~~==Overview==~~

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~~Smt3 belongs~~ to ~~a growing family of ubiquitin-related proteins involved in posttranslational protein modification. Independent studies demonstrate an essential function of Smt3 in~~ the ~~regulation of nucleocytoplasmic transport, and suggest a role in cell-cycle regulation~~. ~~Here we report the high-resolution NMR structure of yeast Smt3 in the complex free form~~. ~~Our comparison of the Smt3 NMR structure with the Smt3 crystal structure in complex with the C-Terminal Ulp1 protease domain revealed large structural differences in the binding surface~~, ~~which~~ is ~~also involved in~~ the ~~Smt3~~-~~Ubc~~-~~9 interaction detected by NMR. The structural differences in the region indicate the important functions of conserved residues in less structurally defined sequences.~~

The line below this paragraph, {{ABSTRACT_PUBMED_12021447}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 12021447 is the PubMed ID number.

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==About this Structure==

1L2N is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L2N OCA].

1L2N is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L2N OCA].

==Reference==

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[[Category: Structure]]

[[Category: Ubiquitin-like protein]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Fri May~~ 2 23:28:25 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 11:33:56 2008''

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-[[Image:1l2n.jpg|left|200px]]
+{{Seed}}
+[[Image:1l2n.png|left|200px]]
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 {{STRUCTURE_1l2n|  PDB=1l2n  |  SCENE=  }}
-'''Smt3 Solution Structure'''
+===Smt3 Solution Structure===
-==Overview==
+<!--
-Smt3 belongs to a growing family of ubiquitin-related proteins involved in posttranslational protein modification. Independent studies demonstrate an essential function of Smt3 in the regulation of nucleocytoplasmic transport, and suggest a role in cell-cycle regulation. Here we report the high-resolution NMR structure of yeast Smt3 in the complex free form. Our comparison of the Smt3 NMR structure with the Smt3 crystal structure in complex with the C-Terminal Ulp1 protease domain revealed large structural differences in the binding surface, which is also involved in the Smt3-Ubc-9 interaction detected by NMR. The structural differences in the region indicate the important functions of conserved residues in less structurally defined sequences.
+The line below this paragraph, {{ABSTRACT_PUBMED_12021447}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 12021447 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_12021447}}
 ==About this Structure==
-L2N is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L2N OCA].
+L2N is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L2N OCA].
 ==Reference==
@@ Line 28: / Line 32: @@
 [[Category: Structure]]
 [[Category: Ubiquitin-like protein]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 23:28:25 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  2 11:33:56 2008''