1m1c: Difference between revisions

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[[Image:1m1c.jpg|left|200px]]
{{Seed}}
[[Image:1m1c.png|left|200px]]


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{{STRUCTURE_1m1c|  PDB=1m1c  |  SCENE=  }}  
{{STRUCTURE_1m1c|  PDB=1m1c  |  SCENE=  }}  


'''Structure of the L-A virus'''
===Structure of the L-A virus===




==Overview==
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The structure of the yeast L-A virus was determined by X-ray crystallography at 3.4 A resolution. The L-A dsRNA virus is 400 A in diameter and contains a single protein shell of 60 asymmetric dimers of the coat protein, a feature common among the inner protein shells of dsRNA viruses and probably related to their unique mode of transcription and replication. The two identical subunits in each dimer are in non-equivalent environments and show substantially different conformations in specific surface regions. The L-A virus decaps cellular mRNA to efficiently translate its own uncapped mRNA. Our structure reveals a trench at the active site of the decapping reaction and suggests a role for nearby residues in the reaction.
The line below this paragraph, {{ABSTRACT_PUBMED_12244300}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 12244300 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12244300}}


==About this Structure==
==About this Structure==
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[[Category: Quai-equivalence]]
[[Category: Quai-equivalence]]
[[Category: Rna-protein interaction]]
[[Category: Rna-protein interaction]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 00:30:44 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 23:00:08 2008''
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