1mbj: Difference between revisions

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[[Image:1mbj.~~jpg~~|left|200px]]

[[Image:1mbj.png|left|200px]]

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~~'''~~MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 3~~'''~~

===MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 3===

~~==Overview==~~

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The ~~DNA-binding domain of c-Myb consists of three imperfect tandem repeats (R1~~, ~~R2 and R3). The three repeats have similar overall architectures~~, ~~each containing a helix-turn-helix variation motif~~. ~~The three conserved tryptophans in each repeat participate in forming a hydrophobic core~~. ~~Comparison of the three repeat structures indicated that cavities are found in the hydrophobic core of R2~~, ~~which~~ is ~~thermally unstable. On complexation with DNA,~~ the orientations of R2 and R3 are fixed by tight binding and their conformations are slightly changed. No significant changes occur in the chemical shifts of R1 consistent with its loose interaction with DNA.

The line below this paragraph, {{ABSTRACT_PUBMED_7796266}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 7796266 is the PubMed ID number.

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==About this Structure==

1MBJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MBJ OCA].

1MBJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MBJ OCA].

==Reference==

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[[Category: Zhang, R.]]

[[Category: Protooncogene product]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May~~ ~~3 00~~:51:42 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 23:37:46 2008''

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-[[Image:1mbj.jpg|left|200px]]
+{{Seed}}
+[[Image:1mbj.png|left|200px]]
 <!--
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 {{STRUCTURE_1mbj|  PDB=1mbj  |  SCENE=  }}
-'''MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 3'''
+===MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 3===
-==Overview==
+<!--
-The DNA-binding domain of c-Myb consists of three imperfect tandem repeats (R1, R2 and R3). The three repeats have similar overall architectures, each containing a helix-turn-helix variation motif. The three conserved tryptophans in each repeat participate in forming a hydrophobic core. Comparison of the three repeat structures indicated that cavities are found in the hydrophobic core of R2, which is thermally unstable. On complexation with DNA, the orientations of R2 and R3 are fixed by tight binding and their conformations are slightly changed. No significant changes occur in the chemical shifts of R1 consistent with its loose interaction with DNA.
+The line below this paragraph, {{ABSTRACT_PUBMED_7796266}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 7796266 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_7796266}}
 ==About this Structure==
-MBJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MBJ OCA].
+MBJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MBJ OCA].
 ==Reference==
@@ Line 35: / Line 39: @@
 [[Category: Zhang, R.]]
 [[Category: Protooncogene product]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 00:51:42 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  2 23:37:46 2008''