1mhk: Difference between revisions

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[[Image:1mhk.gif|left|200px]]
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[[Image:1mhk.png|left|200px]]


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{{STRUCTURE_1mhk|  PDB=1mhk  |  SCENE=  }}  
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'''Crystal Structure Analysis of a 26mer RNA molecule, representing a new RNA motif, the hook-turn'''
===Crystal Structure Analysis of a 26mer RNA molecule, representing a new RNA motif, the hook-turn===




==Overview==
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A crystal structure has been obtained for a 26-nucleotide RNA that contains the loop E sequence from Chromatium minutissimum. Rather than having a loop E-like conformation, it consists of an A-form helix that splits into two separate strands following a sheared A-G base pair. The backbone of the strand containing the G of the A-G pair makes a turn of almost 180 degrees in the space of two nucleotides, and then interacts with the minor groove of the helix from which it originates. Similar structures, which we call hook-turns, occur in 16S and 23S rRNAs. They are found at places where the two strands of a helix separate at an A/G juxtaposition to interact with other sequences.
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{{ABSTRACT_PUBMED_12554875}}


==About this Structure==
==About this Structure==
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[[Category: 180 degree turn]]
[[Category: 180 degree turn]]
[[Category: Helix]]
[[Category: Helix]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 01:02:29 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 23:58:35 2008''

Revision as of 20:58, 2 July 2008

File:1mhk.png

Template:STRUCTURE 1mhk

Crystal Structure Analysis of a 26mer RNA molecule, representing a new RNA motif, the hook-turn

Template:ABSTRACT PUBMED 12554875

About this Structure

Full crystallographic information is available from OCA.

Reference

The crystal structure of a 26-nucleotide RNA containing a hook-turn., Szep S, Wang J, Moore PB, RNA. 2003 Jan;9(1):44-51. PMID:12554875

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