6rhn: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
Line 1: Line 1:
[[Image:6rhn.gif|left|200px]]
{{Seed}}
[[Image:6rhn.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_6rhn|  PDB=6rhn  |  SCENE=  }}  
{{STRUCTURE_6rhn|  PDB=6rhn  |  SCENE=  }}  


'''HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN (HINT) FROM RABBIT WITHOUT NUCLEOTIDE'''
===HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN (HINT) FROM RABBIT WITHOUT NUCLEOTIDE===




==Overview==
<!--
Histidine triad nucleotide-binding protein (HINT), a dimeric purine nucleotide-binding protein from rabbit heart, is a member of the HIT (histidine triad) superfamily which includes HINT homologues and FHIT (HIT protein encoded at the chromosome 3 fragile site) homologues. Crystal structures of HINT-nucleotide complexes demonstrate that the most conserved residues in the superfamily mediate nucleotide binding and that the HIT motif forms part of the phosphate binding loop. Galactose-1-phosphate uridylyltransferase, whose deficiency causes galactosemia, contains tandem HINT domains with the same fold and mode of nucleotide binding as HINT despite having no overall sequence similarity. Features of FHIT, a diadenosine polyphosphate hydrolase and candidate tumour suppressor, are predicted from HINT-nucleotide structures.
The line below this paragraph, {{ABSTRACT_PUBMED_9164465}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 9164465 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_9164465}}


==About this Structure==
==About this Structure==
Line 30: Line 34:
[[Category: Ringe, D.]]
[[Category: Ringe, D.]]
[[Category: Nucleotide-binding protein]]
[[Category: Nucleotide-binding protein]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 22:42:45 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 14:25:22 2008''

Revision as of 11:25, 3 July 2008

File:6rhn.png

Template:STRUCTURE 6rhn

HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN (HINT) FROM RABBIT WITHOUT NUCLEOTIDE

Template:ABSTRACT PUBMED 9164465

About this Structure

6RHN is a Single protein structure of sequence from Oryctolagus cuniculus. Full crystallographic information is available from OCA.

Reference

Crystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins., Brenner C, Garrison P, Gilmour J, Peisach D, Ringe D, Petsko GA, Lowenstein JM, Nat Struct Biol. 1997 Mar;4(3):231-8. PMID:9164465

Page seeded by OCA on Thu Jul 3 14:25:22 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=6rhn&oldid=636092"