2ki5: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
Line 1: Line 1:
[[Image:2ki5.gif|left|200px]]
{{Seed}}
[[Image:2ki5.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2ki5|  PDB=2ki5  |  SCENE=  }}  
{{STRUCTURE_2ki5|  PDB=2ki5  |  SCENE=  }}  


'''HERPES SIMPLEX TYPE-1 THYMIDINE KINASE IN COMPLEX WITH THE DRUG ACICLOVIR AT 1.9A RESOLUTION'''
===HERPES SIMPLEX TYPE-1 THYMIDINE KINASE IN COMPLEX WITH THE DRUG ACICLOVIR AT 1.9A RESOLUTION===




==Overview==
<!--
Treatment of herpes infections with nucleoside analogues requires as an initial step the activation of the compounds by thymidine kinase. As an aid to developing more effective chemotherapy, both for treatment of recurrent herpes infection and in gene therapy systems where thymidine kinase is expressed, two high-resolution X-ray structures of thymidine kinase have been compared: one with the relatively poor substrate aciclovir (Zovirax), the other with a synthetic inhibitor having an N2-substituted guanine. Both compounds have similar binding modes in spite of their size difference and apparently distinct ligand properties.
The line below this paragraph, {{ABSTRACT_PUBMED_9989588}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 9989588 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_9989588}}


==About this Structure==
==About this Structure==
Line 35: Line 39:
[[Category: Herpesviridae]]
[[Category: Herpesviridae]]
[[Category: Viridae]]
[[Category: Viridae]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 09:29:06 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 12:29:16 2008''
Retrieved from "https://proteopedia.org/2ki5"