2f3k: Difference between revisions

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[[Image:2f3k.jpg|left|200px]]
{{Seed}}
[[Image:2f3k.png|left|200px]]


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{{STRUCTURE_2f3k|  PDB=2f3k  |  SCENE=  }}  
{{STRUCTURE_2f3k|  PDB=2f3k  |  SCENE=  }}  


'''Substrate envelope and drug resistance: crystal structure of r01 in complex with wild-type hiv-1 protease'''
===Substrate envelope and drug resistance: crystal structure of r01 in complex with wild-type hiv-1 protease===




==Overview==
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In our previous crystallographic studies of human immunodeficiency virus type 1 (HIV-1) protease-substrate complexes, we described a conserved "envelope" that appears to be important for substrate recognition and the selection of drug-resistant mutations. In this study, the complex of HIV-1 protease with the inhibitor RO1 was determined and comparison with the substrate envelope provides a rationale for mutational patterns.
The line below this paragraph, {{ABSTRACT_PUBMED_16569872}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_16569872}}


==About this Structure==
==About this Structure==
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[[Category: Ro1]]
[[Category: Ro1]]
[[Category: Substrate envelope]]
[[Category: Substrate envelope]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 03:25:25 2008''
 
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