2ush: Difference between revisions

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[[Image:2ush.jpg|left|200px]]
{{Seed}}
[[Image:2ush.png|left|200px]]


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{{STRUCTURE_2ush|  PDB=2ush  |  SCENE=  }}  
{{STRUCTURE_2ush|  PDB=2ush  |  SCENE=  }}  


'''5'-NUCLEOTIDASE FROM E. COLI'''
===5'-NUCLEOTIDASE FROM E. COLI===




==Overview==
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The crystal structure of 5'-nucleotidase (5'-NT) from E. coli, also known as UDP-sugar hydrolase, has been determined at 1.7 A resolution. Two zinc ions are present in the active site, which is located in a cleft between two domains. The dimetal center and a catalytic Asp-His dyad are the main players in the catalytic mechanism. Structure-based sequence comparisons show that the structure also provides a model for animal 5'-NTs, which together with other ectonucleotidases terminate the action of nucleotides as extracellular signaling substances in the nervous system.
The line below this paragraph, {{ABSTRACT_PUBMED_10331872}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 10331872 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10331872}}


==About this Structure==
==About this Structure==
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[[Category: Phosphatase]]
[[Category: Phosphatase]]
[[Category: Udp-sugar hydrolase]]
[[Category: Udp-sugar hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:19:57 2008''
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