2a2j: Difference between revisions

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[[Image:2a2j.gif|left|200px]]
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[[Image:2a2j.png|left|200px]]


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{{STRUCTURE_2a2j|  PDB=2a2j  |  SCENE=  }}  
{{STRUCTURE_2a2j|  PDB=2a2j  |  SCENE=  }}  


'''Crystal structure of a putative pyridoxine 5'-phosphate oxidase (Rv2607) from Mycobacterium tuberculosis'''
===Crystal structure of a putative pyridoxine 5'-phosphate oxidase (Rv2607) from Mycobacterium tuberculosis===




==Overview==
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The three-dimensional structure of Rv2607, a putative pyridoxine 5'-phosphate oxidase (PNPOx) from Mycobacterium tuberculosis, has been determined by X-ray crystallography to 2.5 A resolution. Rv2607 has a core domain similar to known PNPOx structures with a flavin mononucleotide (FMN) cofactor. Electron density for two FMN at the dimer interface is weak despite the bright yellow color of the protein solution and crystal. The shape and size of the putative binding pocket is markedly different from that of members of the PNPOx family, which may indicate some significant changes in the FMN binding mode of this protein relative to members of the family.
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{{ABSTRACT_PUBMED_16374842}}


==About this Structure==
==About this Structure==
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[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Xmtb]]
[[Category: Xmtb]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:12:31 2008''

Revision as of 14:12, 27 July 2008

File:2a2j.png

Template:STRUCTURE 2a2j

Crystal structure of a putative pyridoxine 5'-phosphate oxidase (Rv2607) from Mycobacterium tuberculosis

Template:ABSTRACT PUBMED 16374842

About this Structure

2A2J is a Single protein structure of sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

Crystal structure of a putative pyridoxine 5'-phosphate oxidase (Rv2607) from Mycobacterium tuberculosis., Pedelacq JD, Rho BS, Kim CY, Waldo GS, Lekin TP, Segelke BW, Rupp B, Hung LW, Kim SI, Terwilliger TC, Proteins. 2006 Mar 15;62(3):563-9. PMID:16374842

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