1sty: Difference between revisions

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{{STRUCTURE_1sty|  PDB=1sty  |  SCENE=  }}  
{{STRUCTURE_1sty|  PDB=1sty  |  SCENE=  }}  


'''THE ALPHA ANEURISM: A STRUCTURAL MOTIF REVEALED IN AN INSERTION MUTANT OF STAPHYLOCOCCAL NUCLEASE'''
===THE ALPHA ANEURISM: A STRUCTURAL MOTIF REVEALED IN AN INSERTION MUTANT OF STAPHYLOCOCCAL NUCLEASE===




==Overview==
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The x-ray crystal structure of a mutant of staphylococcal nuclease that contains a single glycine residue inserted in the C-terminal alpha-helix has been solved to 1.67 A resolution and refined to a crystallographic R value of 0.170. This inserted glycine residue is accommodated in the alpha-helix by formation of a previously uncharacterized bulge, which we term the alpha aneurism. A conformational search of known protein structures has identified the alpha aneurism in a number of protein families, including the histocompatibility antigens and hemoglobins.
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==About this Structure==
==About this Structure==
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[[Category: Keefe, L J.]]
[[Category: Keefe, L J.]]
[[Category: Lattman, E E.]]
[[Category: Lattman, E E.]]
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