2pob: Difference between revisions

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[[Image:2pob.jpg|left|200px]]
{{Seed}}
[[Image:2pob.png|left|200px]]


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{{STRUCTURE_2pob|  PDB=2pob  |  SCENE=  }}  
{{STRUCTURE_2pob|  PDB=2pob  |  SCENE=  }}  


'''PPARgamma Ligand binding domain complexed with a farglitazar analogue gw4709'''
===PPARgamma Ligand binding domain complexed with a farglitazar analogue gw4709===




==Overview==
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PPARgamma-activating thiazolidinediones and carboxylic acids such as farglitazar exert their anti-diabetic effects in part in PPARgamma rich adipose. Both pro- and anti-adipogenic PPARgamma ligands promote glucose and lipid lowering in animal models of diabetes. Herein, we disclose representatives of an array of 160 farglitazar analogues with atypical inverse agonism of PPARgamma in mature adipocytes.
The line below this paragraph, {{ABSTRACT_PUBMED_17533125}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 17533125 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17533125}}


==About this Structure==
==About this Structure==
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[[Category: Nuclear receptor,ppar]]
[[Category: Nuclear receptor,ppar]]
[[Category: Pparg]]
[[Category: Pparg]]
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