2i2t: Difference between revisions

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[[Image:2i2t.~~gif~~|left|200px]]

[[Image:2i2t.png|left|200px]]

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~~'''~~Crystal Structure of Ribosome with messenger RNA and the Anticodon stem-loop of P-site tRNA. This file contains the 50s subunit of one 70s ribosome. The entire crystal structure contains two 70s ribosomes and is described in remark 400.~~'''~~

===Crystal Structure of Ribosome with messenger RNA and the Anticodon stem-loop of P-site tRNA. This file contains the 50s subunit of one 70s ribosome. The entire crystal structure contains two 70s ribosomes and is described in remark 400.===

~~==Overview==~~

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~~Protein synthesis requires the accurate positioning of mRNA and tRNA in the peptidyl~~-~~tRNA site of the ribosome. Here we describe x~~-~~ray crystal structures of~~ the ~~intact bacterial ribosome from Escherichia coli in a complex with mRNA and~~ the ~~anticodon stem-loop of P-site tRNA~~. ~~At 3~~.~~5-A resolution~~, ~~these structures reveal rearrangements in~~ the ~~intact ribosome that clamp P-site tRNA and mRNA on the small ribosomal subunit~~. ~~Binding of the anticodon stem~~-~~loop of P~~-~~site tRNA to the ribosome is sufficient to lock the head of the small ribosomal subunit in a single conformation, thereby preventing movement of mRNA and tRNA before mRNA decoding.~~

The line below this paragraph, {{ABSTRACT_PUBMED_17038497}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 17038497 is the PubMed ID number.

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==About this Structure==

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[[Category: Protein-nucleic acid complex]]

[[Category: Ribosome]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun ~~May 4 07~~:00:21 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 21:29:19 2008''

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-[[Image:2i2t.gif|left|200px]]
+{{Seed}}
+[[Image:2i2t.png|left|200px]]
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 {{STRUCTURE_2i2t|  PDB=2i2t  |  SCENE=  }}
-'''Crystal Structure of Ribosome with messenger RNA and the Anticodon stem-loop of P-site tRNA. This file contains the 50s subunit of one 70s ribosome. The entire crystal structure contains two 70s ribosomes and is described in remark 400.'''
+===Crystal Structure of Ribosome with messenger RNA and the Anticodon stem-loop of P-site tRNA. This file contains the 50s subunit of one 70s ribosome. The entire crystal structure contains two 70s ribosomes and is described in remark 400.===
-==Overview==
+<!--
-Protein synthesis requires the accurate positioning of mRNA and tRNA in the peptidyl-tRNA site of the ribosome. Here we describe x-ray crystal structures of the intact bacterial ribosome from Escherichia coli in a complex with mRNA and the anticodon stem-loop of P-site tRNA. At 3.5-A resolution, these structures reveal rearrangements in the intact ribosome that clamp P-site tRNA and mRNA on the small ribosomal subunit. Binding of the anticodon stem-loop of P-site tRNA to the ribosome is sufficient to lock the head of the small ribosomal subunit in a single conformation, thereby preventing movement of mRNA and tRNA before mRNA decoding.
+The line below this paragraph, {{ABSTRACT_PUBMED_17038497}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 17038497 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_17038497}}
 ==About this Structure==
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 [[Category: Protein-nucleic acid complex]]
 [[Category: Ribosome]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 07:00:21 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 21:29:19 2008''