2ggp: Difference between revisions

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[[Image:2ggp.gif|left|200px]]
{{Seed}}
[[Image:2ggp.png|left|200px]]


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{{STRUCTURE_2ggp|  PDB=2ggp  |  SCENE=  }}  
{{STRUCTURE_2ggp|  PDB=2ggp  |  SCENE=  }}  


'''Solution structure of the Atx1-Cu(I)-Ccc2a complex'''
===Solution structure of the Atx1-Cu(I)-Ccc2a complex===




==Overview==
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Cellular systems allow transition-metal ions to reach or leave the cell or intracellular locations through metal transfer between proteins. By coupling mutagenesis and advanced NMR experiments, we structurally characterized the adduct between the copper chaperone Atx1 and the first copper(I)-binding domain of the Ccc2 ATPase. Copper was required for the interaction. This study provides an understanding of metal-mediated protein-protein interactions in which the metal ion is essential for the weak, reversible interaction between the partners.
The line below this paragraph, {{ABSTRACT_PUBMED_16732294}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 16732294 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16732294}}


==About this Structure==
==About this Structure==
2GGP is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GGP OCA].  
2GGP is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GGP OCA].  


==Reference==
==Reference==
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[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Structural proteomics in europe]]
[[Category: Structural proteomics in europe]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Apr 13 08:19:43 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:02:02 2008''

Revision as of 20:02, 27 July 2008

File:2ggp.png

Template:STRUCTURE 2ggp

Solution structure of the Atx1-Cu(I)-Ccc2a complex

Template:ABSTRACT PUBMED 16732294

About this Structure

2GGP is a Protein complex structure of sequences from Saccharomyces cerevisiae. Full experimental information is available from OCA.

Reference

The Atx1-Ccc2 complex is a metal-mediated protein-protein interaction., Banci L, Bertini I, Cantini F, Felli IC, Gonnelli L, Hadjiliadis N, Pierattelli R, Rosato A, Voulgaris P, Nat Chem Biol. 2006 Jul;2(7):367-8. Epub 2006 May 28. PMID:16732294

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