3bqp: Difference between revisions

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[[Image:3bqp.jpg|left|200px]]
{{Seed}}
[[Image:3bqp.png|left|200px]]


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{{STRUCTURE_3bqp|  PDB=3bqp  |  SCENE=  }}  
{{STRUCTURE_3bqp|  PDB=3bqp  |  SCENE=  }}  


'''Crystal Structure of Human Saposin D (orthorhombic)'''
===Crystal Structure of Human Saposin D (orthorhombic)===




==Overview==
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Saposin D is a sphingolipid activator protein required for the lysosomal breakdown of ceramide to a fatty acid and sphingosine by acid ceramidase. The crystal structure of saposin D has been determined in two different crystal forms, resulting in a total of six crystallographically independent views of this small 80-amino-acid protein. All of the structures are highly similar and reveal the monomeric form of the saposin fold previously seen in the crystal structures of saposins A and C. Saposin D is slightly more compact than the related saposins A and C owing to a slight repositioning of the ;stem' and ;hairpin' regions of the protein.
The line below this paragraph, {{ABSTRACT_PUBMED_18453694}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_18453694}}


==About this Structure==
==About this Structure==
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[[Category: Sphingolipid activator protein]]
[[Category: Sphingolipid activator protein]]
[[Category: Sphingolipid metabolism]]
[[Category: Sphingolipid metabolism]]
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