1urx: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
Line 1: Line 1:
[[Image:1urx.gif|left|200px]]
{{Seed}}
[[Image:1urx.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1urx|  PDB=1urx  |  SCENE=  }}  
{{STRUCTURE_1urx|  PDB=1urx  |  SCENE=  }}  


'''CRYSTALLOGRAPHIC STRUCTURE OF BETA-AGARASE A IN COMPLEX WITH OLIGOAGAROSE'''
===CRYSTALLOGRAPHIC STRUCTURE OF BETA-AGARASE A IN COMPLEX WITH OLIGOAGAROSE===




==Overview==
<!--  
Agarose is a gel-forming polysaccharide with an alpha-L(1,4)-3,6-anhydro-galactose, beta-D(1,3)-galactose repeat unit, from the cell walls of marine red algae. beta-agarase A, from the Gram-negative bacterium Zobellia galactanivorans, is secreted to the external medium and degrades agarose with an endo-mechanism. The structure of the inactive mutant beta-agarase A-E147S in complex with agaro-octaose has been solved at 1.7 A resolution. Two oligosaccharide chains are bound to the protein. The first one resides in the active site channel, spanning subsites -4 to -1. A second oligosaccharide binding site, on the opposite side of the protein, was filled with eight sugar units, parallel to the active site. The crystal structure of the beta-agarase A with agaro-octaose provides detailed information on agarose recognition in the catalytic site. The presence of the second, parallel, binding site suggests that the enzyme might be able to unwind the double-helical structure of agarose prior to the catalytic cleavage.
The line below this paragraph, {{ABSTRACT_PUBMED_15062085}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 15062085 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_15062085}}


==About this Structure==
==About this Structure==
Line 33: Line 37:
[[Category: Glycoside hydrolase]]
[[Category: Glycoside hydrolase]]
[[Category: Two binding-site]]
[[Category: Two binding-site]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 11:36:22 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:44:59 2008''

Revision as of 21:45, 27 July 2008

File:1urx.png

Template:STRUCTURE 1urx

CRYSTALLOGRAPHIC STRUCTURE OF BETA-AGARASE A IN COMPLEX WITH OLIGOAGAROSE

Template:ABSTRACT PUBMED 15062085

About this Structure

1URX is a Single protein structure of sequence from Zobellia galactanivorans. Full crystallographic information is available from OCA.

Reference

Parallel substrate binding sites in a beta-agarase suggest a novel mode of action on double-helical agarose., Allouch J, Helbert W, Henrissat B, Czjzek M, Structure. 2004 Apr;12(4):623-32. PMID:15062085

Page seeded by OCA on Mon Jul 28 00:44:59 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=1urx&oldid=674133"