1ntx: Difference between revisions

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[[Image:1ntx.gif|left|200px]]
{{Seed}}
[[Image:1ntx.png|left|200px]]


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{{STRUCTURE_1ntx|  PDB=1ntx  |  SCENE=  }}  
{{STRUCTURE_1ntx|  PDB=1ntx  |  SCENE=  }}  


'''SECONDARY STRUCTURE DETERMINATION FOR ALPHA-NEUROTOXIN FROM DENDROASPIS POLYLEPIS POLYLEPIS BASED ON SEQUENCE SPECIFIC PROTON NUCLEAR MAGNETIC RESONANCE ASSIGNMENTS'''
===SECONDARY STRUCTURE DETERMINATION FOR ALPHA-NEUROTOXIN FROM DENDROASPIS POLYLEPIS POLYLEPIS BASED ON SEQUENCE SPECIFIC PROTON NUCLEAR MAGNETIC RESONANCE ASSIGNMENTS===




==Overview==
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Sequence-specific assignments are presented for the polypeptide backbone protons and a majority of the amino-acid-side-chain protons of alpha-neurotoxin from Dendroaspis polylepis polylepis, and individual amide proton-exchange rates with the solvent are reported. The secondary structure and the hydrogen-bonding patterns in the regular secondary structure elements are deduced from nuclear Overhauser effects and the sequence locations of the slowly exchanging amide protons. The molecule includes a three-stranded antiparallel beta-sheet, and there are indications that two additional short chain segments are arranged in an antiparallel beta-sheet. These structural elements are similar, but not identical, to either the secondary structure reported for erabutoxin b in single crystals, or the solution structure of cytotoxin CTXIIb from Naja mossambica mossambica.
The line below this paragraph, {{ABSTRACT_PUBMED_2847926}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 2847926 is the PubMed ID number.
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{{ABSTRACT_PUBMED_2847926}}


==About this Structure==
==About this Structure==
1NTX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Dendroaspis_polylepis_polylepis Dendroaspis polylepis polylepis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA].  
1NTX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Dendroaspis_polylepis_polylepis Dendroaspis polylepis polylepis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTX OCA].  


==Reference==
==Reference==
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[[Category: Wuthrich, K.]]
[[Category: Wuthrich, K.]]
[[Category: Neurotoxin]]
[[Category: Neurotoxin]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 02:58:22 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 01:53:42 2008''

Revision as of 22:53, 27 July 2008

File:1ntx.png

Template:STRUCTURE 1ntx

SECONDARY STRUCTURE DETERMINATION FOR ALPHA-NEUROTOXIN FROM DENDROASPIS POLYLEPIS POLYLEPIS BASED ON SEQUENCE SPECIFIC PROTON NUCLEAR MAGNETIC RESONANCE ASSIGNMENTS

Template:ABSTRACT PUBMED 2847926

About this Structure

1NTX is a Single protein structure of sequence from Dendroaspis polylepis polylepis. Full experimental information is available from OCA.

Reference

Secondary structure determination for alpha-neurotoxin from Dendroaspis polylepis polylepis based on sequence-specific 1H-nuclear-magnetic-resonance assignments., Labhardt AM, Hunziker-Kwik EH, Wuthrich K, Eur J Biochem. 1988 Nov 1;177(2):295-305. PMID:2847926

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