2nui: Difference between revisions

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[[Image:2nui.gif|left|200px]]
{{Seed}}
[[Image:2nui.png|left|200px]]


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{{STRUCTURE_2nui|  PDB=2nui  |  SCENE=  }}  
{{STRUCTURE_2nui|  PDB=2nui  |  SCENE=  }}  


'''X-ray Structure of synthetic [D83A]RNase A'''
===X-ray Structure of synthetic [D83A]RNase A===




==Overview==
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The total chemical synthesis of RNase A using modern chemical ligation methods is described, illustrating the significant advances that have been made in chemical protein synthesis since Gutte and Merrifield's pioneering preparation of RNase A in 1969. The identity of the synthetic product was confirmed through rigorous characterization, including the determination of the X-ray crystal structure to 1.1 Angstrom resolution. (c) 2007 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 90:278-286, 2008.This article was originally published online as an accepted preprint. The "Published Online" date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com.
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{{ABSTRACT_PUBMED_17610259}}


==About this Structure==
==About this Structure==
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[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Synthetic protein]]
[[Category: Synthetic protein]]
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Revision as of 23:34, 27 July 2008

File:2nui.png

Template:STRUCTURE 2nui

X-ray Structure of synthetic [D83A]RNase A

Template:ABSTRACT PUBMED 17610259

About this Structure

2NUI is a Single protein structure. Full crystallographic information is available from OCA.

Reference

Total synthesis by modern chemical ligation methods and high resolution (1.1 A) X-ray structure of ribonuclease A., Boerema DJ, Tereshko VA, Kent SB, Biopolymers. 2008;90(3):278-86. PMID:17610259

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