2f6v: Difference between revisions

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[[Image:2f6v.gif|left|200px]]
{{Seed}}
[[Image:2f6v.png|left|200px]]


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{{STRUCTURE_2f6v|  PDB=2f6v  |  SCENE=  }}  
{{STRUCTURE_2f6v|  PDB=2f6v  |  SCENE=  }}  


'''Protein tyrosine phosphatase 1B with sulfamic acid inhibitors'''
===Protein tyrosine phosphatase 1B with sulfamic acid inhibitors===




==Overview==
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High-throughput screening of the P&amp;GP corporate repository against several protein tyrosine phosphatases identified the sulfamic acid moiety as potential phosphotyrosine mimetic. Incorporation of the sulfamic acid onto a 1,2,3,4-tetrahydroisoquinoline scaffold provided a promising starting point for PTP1B inhibitor design.
The line below this paragraph, {{ABSTRACT_PUBMED_16386905}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_16386905}}


==About this Structure==
==About this Structure==
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[[Category: Tetrahydroisoquinoline]]
[[Category: Tetrahydroisoquinoline]]
[[Category: Tyrosine]]
[[Category: Tyrosine]]
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