2a5w: Difference between revisions

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[[Image:2a5w.gif|left|200px]]
{{Seed}}
[[Image:2a5w.png|left|200px]]


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{{STRUCTURE_2a5w|  PDB=2a5w  |  SCENE=  }}  
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'''Crystal structure of the oxidized gamma-subunit of the dissimilatory sulfite reductase (DsrC) from Archaeoglobus fulgidus'''
===Crystal structure of the oxidized gamma-subunit of the dissimilatory sulfite reductase (DsrC) from Archaeoglobus fulgidus===




==Overview==
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The X-ray structure of the gamma-subunit of the dissimilatory sulfite reductase (DsrC) from Archaeoglobus fulgidus was determined at 1.12 and 2.1A resolution, in the two crystal forms named DsrC(nat) and DsrC(ox) the latter being cocrystallized with the oxidizing agent tert-butyl hydroperoxide. The fold corresponds to that of the homologous protein from Pyrobaculum aerophilum but is significantly more compact. The most interesting, highly conserved C-terminal arm adopts a well-defined conformation in A. fulgidus DsrC in contrast to the completely disordered conformation in P. aerophilum DsrC. The functional relevance of both conformations and of a potentially redox-active disulfide bond between the strictly invariant Cys103 and Cys114 are discussed.
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{{ABSTRACT_PUBMED_16098517}}


==About this Structure==
==About this Structure==
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[[Category: Weiss, M S.]]
[[Category: Weiss, M S.]]
[[Category: Orthogonal helix bundle]]
[[Category: Orthogonal helix bundle]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 18:38:46 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 03:18:31 2008''

Revision as of 00:18, 28 July 2008

File:2a5w.png

Template:STRUCTURE 2a5w

Crystal structure of the oxidized gamma-subunit of the dissimilatory sulfite reductase (DsrC) from Archaeoglobus fulgidus

Template:ABSTRACT PUBMED 16098517

About this Structure

2A5W is a Single protein structure of sequence from Archaeoglobus fulgidus dsm 4304. Full crystallographic information is available from OCA.

Reference

X-ray structure of the gamma-subunit of a dissimilatory sulfite reductase: fixed and flexible C-terminal arms., Mander GJ, Weiss MS, Hedderich R, Kahnt J, Ermler U, Warkentin E, FEBS Lett. 2005 Aug 29;579(21):4600-4. PMID:16098517

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