1w33: Difference between revisions

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[[Image:1w33.gif|left|200px]]
{{Seed}}
[[Image:1w33.png|left|200px]]


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{{STRUCTURE_1w33|  PDB=1w33  |  SCENE=  }}  
{{STRUCTURE_1w33|  PDB=1w33  |  SCENE=  }}  


'''BBCRASP-1 FROM BORRELIA BURGDORFERI'''
===BBCRASP-1 FROM BORRELIA BURGDORFERI===




==Overview==
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Borrelia burgdorferi, a spirochete transmitted to human hosts during feeding of infected Ixodes ticks, is the causative agent of Lyme disease. Serum-resistant B. burgdorferi strains cause a chronic, multisystemic form of the disease and bind complement factor H (FH) and FH-like protein 1 (FHL-1) on the spirochete surface. Here we report the atomic structure for the key FHL-1- and FH-binding protein BbCRASP-1 and reveal a homodimer that presents a novel target for drug design.
The line below this paragraph, {{ABSTRACT_PUBMED_15711564}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 15711564 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15711564}}


==About this Structure==
==About this Structure==
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[[Category: Membrane protein]]
[[Category: Membrane protein]]
[[Category: Tick]]
[[Category: Tick]]
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